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doi: 10.1136/annrheumdis-2015-207776 267 RosenzwajgMLorenzonRCacoubPPhamHPPitoisetFSoufiKEet al
Placebo-Controlled Studies With DPP-4 Inhibition as Add-on to Ongoing Thiazolidinedione Therapy When added to on-going therapy with a thiazolidinedione in subjects with type 2 diabetes, the DPP-4 inhibitors were studied in 2426 week placebo-controlled studies with a total number of 2,146 subjects [Table 2
POMC neuron ablation was performed on 5-week-old iDTR:: Pomc -Cre mice by intracerebroventricular (i.c.v.) infusion of 2.5 ng of diphtheria toxin (DT) dissolved in 2.0 L of saline, followed by a 2-week period to ensure complete cell-lineage ablation [11-13]
10.1007/s00125-009-1440-6 39 DadwalP.MahmudN.SinaiL.AzimiA.FattM.WondisfordF
For these patients, the goal of personalization is to prescribe just enough medication to achieve targeted results but not so much that the cure feels worse than the disease
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